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CyCa-dds employs a unique, non-endocytic mechanism that delivers molecular payloads into live cells by mechanically penetrating the cell membrane without damaging the cells. It translocates through the bilayer of the cell membrane reducing drug dosage and increasing functionality of therapeutic molecules.The nanomachine is non-toxic, negatively charged and has low immunogenicity.

Highly efficient drug delivery system based on novel non endocytic cell entry mechanism

Cancer cells of CyCa delivery device (CyCa-dd) are presence in(a) and absence in(b)

(a)
(b)

Green: CyCa-dd; Red: cell membrane; Blue: Nucleus

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